✅ 32 yrs. Nurse presented in ED following a needle stick injury from an HBs Ag positive pt + Lab test: her anti-HBs ab titer <10 following 3 months her last booster dose + Most appropriate important intervention >> Hepatitis B immunoglobulin.
✅ 23 yrs man presented with intermittent diarrhea, bloating, and abdominal pain for 3 weeks following a holiday in vietnam + On exam: Wt loss, mild abdominal tenderness + Lab test: Raised CRP + Most likely Dx >> Giardiasis.
✅ 18 yrs lady show farm worker presented with nausea, vomiting, and diarrhea for a few days + onLab test: Hb%: 82 g/l (Fragmented red cells on film) + Platelet count: 61×10^9/l + Creatinine: RAISED + most likely dx >> Hemolytic Uremic syndrome.
✅ 74 elderly pt presented with lumbar pain and Rt humerous pain & getting pallor + GP said: his renal function is deteriorating + Lab test: Hb%: 92 gm/l + Creatine raised + with raised Globulin fraction in blood + Most likely diagnosis >> Multiple Myeloma
✅ 42 yr. Bar owner presented with confusion, short-term memory loss, and diplopia + On exam: Lateral Gaze palsy, nystagmus, and unsteady gait + Lab test: Anemia; Low platelet count + Most likely Dx >> Wernicke’s encephalopathy.
✅ 45 yr pt known to have cyclical Vomiting syndrome presented with diarrhea following starting an anti-emetic + No other past medical or allergic history + Most likely medication to be causing this pt’s symptoms >> Metoclopramide.
✅ 45 yrs. Known to have DM, HTN lady now presented with sudden painless visual loss affecting Lt eye + Ophthalmoscopy shows: Multiple Flame shape hemorrhage + Most likely cause of pt’s symptoms >> Central retinal vein occlusion
Image: CRVO
✅ 26 yrs heroin addict brought unconscious to ED + On exam: Pinpoint pupil, low BP, RR: 6 br/min + O2 90% on 10 liters oxygen + Most appropriate next step >> Naloxone.
★ Naloxone is a competitive opioid receptor inhibitor, usually used as an antidote for opioid overdose.
✅ 21 yrs. PT from a traveling family presented with headache, nosebleed, HTN + Differential BP in 2 arms + Pulse in Foot appears to be diminished + CXR shows: the following + Most likely cause of PT’s symptoms >> Coarctation of the Aorta
Image: Coarctation of Aorta
Interpretation: Rib notching is pointed by red arrows, and Figure “3” is pointed by yellow, blue, and green arrows.
★ Travelling families may fail to engage with medical services accounting for this patient’s delayed presentation.
✅ 32 yr Pakistani pregnant lady presented with Irregular palpitation, SOB + H/O frequent illness as a child + ECG: Atrial fibrillation, ventricular rate: 110 bpm + Most likely cause of pt’s atrial fibrillation >> Mitral stenosis. (Dx: Rheumatic Heart Disease)
✅ 31 yrs pt presented with erythematous scaling skin rash over the scalp and extensor surface of body + On exam: Nail pitting + Most likely dx >> Psoriasis.
Image: Psoriasis Rash
✅ 48 YRS lady with Known RA presented with dry mouth, dry eyes, weakness + Lab test: Low K+, Low HCO3-; Urine analysis: (Blood negative, protein positive) + Most likely dx >> Renal Tubular acidosis Type-1.
★ Pt with autoimmune Rheumatological diseased pt usually presented with RTA type 1
✅ 73 yr pt known to have chronic stable angina and Class 2 heart failure and Bronchial asthma + Taking GTN for chest pain and salmeterol, fluticasone for Bronchial asthma+ HR: 85 bpm + Most appropriate intervention for this pt’s angina >> Ivabradine.
★ Beta blocker is contraindicated in asthma pt.
✅ Known CKD pt presented with lethargy, bone pain + Lab test: Low Hb%, High Creatinine, and High phosphate + Most likely cause of pt’s presentation >> Secondary Hyperparathyroidism.
✅ 49 yrs pt presented with sensory loss affecting both feet and frequent tripping + On exam: Loss of fine touch proprioception and vibration sense, loss of ankle jerk + EMG: Positive sharp waves and fibrillation potential + Lab test: Low Hb%, Low platelet count + Most likely cause of pt’s neuropathy >> Alcoholic neuropathy.
★ Anemia and thrombocytopenia are consistent with Chronic liver disease Due to alcoholism.
✅ Elderly pt present with worsening confusion and cough for last 5 days + On exam: Crackles in the Rt lung base + Lab test: Raised WBC, Low Sodium: 128 mmol/l + Most appropriate next step >> Fluid restriction. (Pt developed pneumonia induced SIADH )
✅ 19 yr boy presented with evening fever, joint pains erythematous rash on chest and thigh + On exam: Intermittent chest pain + Lab test: Raised WBC, Raised ESR + Most likely dx >> Adult onset still disease.
★ M. avium usually causes pulmonary infection in pt who has underlying lung disease.
✅ 22 yr pt brought to ED following PCM overdose of unknown quantity + Feels nauseated, abdominal tenderness + Lab test: Raised ALT: 2732, high Cr, High INR, Low platelet count + Most appropriate intervention >> Acetylcysteine.
✅ 24 yr ladt present with Lt loin pain and swing fever + On exam: Raised ™, Lt loin tenderness + Lab test: Raised WBC + Most likely dx >> Pyelonephritis.
✅ 27 27-year-old pt presented with severe headache, myalgia, and fever following. Hiking to northwest Of the USA + On exam: maculopapular rash on the wrist and forearm + Small necrotic insect bite on the left ankle + Most likely dx >> Rocky Mountain spotted fever.
✅23 yr pt brought to ED following a collapse in a night club + On exam: SOB, chest pain, confusion, Blue color skin + Oxygen saturation: 86% on 60% inspired oxygen + Lab test: pa(O2): 50 kPa + Most appropriate intervention >> Methylene blue.
★ Methylene Blue is the accepted first-line intervention for the methemoglobinemia
✅ 49 yrs afro-Caribbean man presented with an average BP 155/92 mmHg on a 24-hr recording + ECG and ECHO normal + Most appropriate treatment for this pt’s Hypertension >> Amlodipine.
✅ 74 yrs pt now on 60 mg steroid present with severe Bitemporal headache, jaw pain + H/O intermittent night sweat, one episode of temporarily lost vision on her left eye + On exam: temporal artery tenderness on palpation + Lab test: Raised ESR + Most useful investigation >> Temporal artery biopsy (Dx: Temporal arteritis)
✅ Risk factor for complete /Successful suicide:
★Umeployment
★ Traumatic life event( Divorce, break up)
★Chronic physical pain
★ Mental illness
★Excessive drinking
★Recent admission in prison service.
✅ 53 yr CKD pt undergoing hemodialysis presented with tiredness + looks pallor despite taking oral iron + Lab test: Low Hb, High creatine + Most appropriate next step >> IV iron infusion.
✅ 52 yr taxi driver presents with severe daytime sleepiness and nighttime snoring with H/o intermittent apneic spell + On exam: BMI: 35kg/m2, Epworth sleepiness score: 18 + Most appropriate intervention >> Nocturnal continue positive airway pressure.
✅ 24 yr pt presented with severe unremitting headaches for a few months + On exam: looks Tired, Bitemporal visual field loss + Most likely diagnosis >> Meningioma
★ MRI T1 reveals homogenous enhancement of a well-circumscribed tumor rising from the dura at the skull base.
Image: MRI of Meningioma At the base of Skull
✅ 32 yr known HIV pt presented with drowsiness, headache, and neck stiffness + On exam: Pt has a cough, Bilateral 6th CN palsy+ Lab test: Raised CSF pressured CSF protein and CSF microscopy: Lymphocytic pleocytosis + CT head with contrast: Leptomeningeal enhancement + Most likely dx >> Tuberculous meningitis.
✅ 39 yr lady presented with hemoptysis + Has sinusitis, HTN + On exam: Inspiratory crackles + Lab test: CXR: Patchy interstitial shadowing through both lungs; Urine: (Blood 3+, protein 2+) + Autoantibody most likely to be found >> Classic C-Anca (Dx: Granulomatosis and polyangiitis)
✅ 59 yr pt presented with Rt-sided dull chest pain and SOB + CT chest: Accumulation of fluid on rt side of Chest + Most likely dx >> Rt pleural effusion.
Image: Ct chest: Rt sided Pleural effusion (Pointed By arrow)
✅ 71 yr pt presented with a H/O 30 mins episode of Lt sided facial weakness, weight loss, night sweat, intermittent fever + On exam: Moderate splenomegaly + Lab test: raised Creatinine, Immunoglobulin electrophoresis: Immunoglobulin (IgM) paraprotein band + Most likely dx >> Waldenstrom macroglobulinemia.
✅ 34 pt presented with wt gain, HTN and DM + Lab test: Low K+, High HCO3-, High 24-hrs urinary cortisol + MRI: no pitytary adenoma seen + Most likely cause of pt’s biochemistry results >> Bronchial Carcinoid.
★ Bronchial carcinoid tumors are known to secrete ACTH and May lead to the development of Cushing syndrome.
✅ 27 yr pt presented with a rapidly enlarging mole on the left forearm + Pt said: it’s painful and itchy + Most likely dx >> Malignant Melanoma.
Image: Malignant Melanoma
✅ 35 yr pt presented with loss of appetite, early satiety, dyspepsia following small bowel resection for Crohn’s disease + On exam: Abdomen is mildly distended + Hydrogen breath test: positive + Most appropriate intervention >> Rifaximin. (Dx: Bacterial Overgrowth syndrome)
✅ 31 yrs drug abuser presented with fever, facial spasms, neck stiffness, and unable to swallow + On exam: injection wound noted on her left foot surrounded by erythema + Lab tests: Raised WBC count + Most likely dx >> Botulism.
★Early dx is crucial for the administration of tetanus antitoxin
★Most pt are considered for prophylactic sedation, intubation, and ventilation.
✅ 28 yr man presented with H/O recurrent lower RTI + CT chest: Thickened dilated bronchi with some displaying the signet ring + Most likely cause of pt’s symptoms >> Pertussis infection as a child.
★ 40% Cases of bronchiectasis are said to be following viral infection:
Image: CT chest shows: Cystic lesion and Signet ring lesion
✅ 27 yrs pt presented with central chest pain worsened by lying down following a cold flu + ECG: Concave ST-elevation + Most likely dx >> Acute pericarditis
✅ 45 lady presented with weight gain, lethargy, menorrhagia + On exam: BP: 150/90 mmHg + Lab test: High TSH with and High triglyceride level + Most appropriate next step for managing this pt’s lipid level >> Thyroxine, then review lipids in 3 months.
✅ 72 yr previously independent pt presented with fractured femur neck + Now confused and deemed not to have capacity + Most important with respect to proceeding to surgery >> Proceeding in the best interests of the pt.
★Unless the advance directive has been issued, the treating team decides to proceed with therapy according to the patient’s best interest.
✅ 54 yrs pt referred by GP due to worsening renal function following taking chinses herbal xi Xin + Lab test: Low HB, Raised Creatinine, and high Urine protein: creatinine ratio + Most likely dx >> Chronic interstitial nephritis.
★Other causes of interstitial nephritis:
✅ 24 yr pt presented with a painless ulcer on the glans penis following unprotected sex in Thailand trip + Most likely dx >> Syphilis.
★ A single dose of IM penicillin is the recommended treatment.